Therapeutic potential of naringenin in the management of CVS and related problems: A comprehensive review

According to epidemiological research, Western-style food patterns are among the factors that influence the emergence of diabetes, dyslipidemia, and cardiovascular diseases. According to recent research, a high-fat diet is responsible for the development of cardiovascular risk in both humans and animals. It has been demonstrated that dietary components derived from plants, such as polyphenolic chemicals (such as flavonoids, anthocyanines, and phenolic acids), may have health benefits for the therapy of obesity, hypertension, and cardiovascular illnesses. Among these bioactive substances, flavonoids make up a significant fraction, and another of the most considerable flavonoids is naringenin. Naringenin lowers elevated plasma levels and has a vasodilation effect, making it useful in the treatment of atherosclerosis and hypertension. It is a good scavenger of free radicals and can prevent oxidative stress. The mechanisms and pharmacology of naringenin as a potential bioactive compound against cardiovascular diseases will be discussed in this article.