Advances in Bone-Targeted Drug Delivery Systems: A Review of Bisphosphonates, Nanoparticles, Liposomes, Nanocarriers, and Radiopharmaceuticals

Abstract: This review article highlights the latest advancements in bone-targeted drug delivery systems, including bisphosphonates, calcium phosphate nanoparticles, liposomes, nanocarriers, and radiopharmaceuticals. These drug delivery systems have been extensively explored for the treatment of various bone diseases, such as osteoporosis and bone cancer. This paper will review the current bone-targeted delivery systems and future prospects of bone-targeted drug delivery systems. The article also discusses the potential of these systems in the delivery of gene therapy agents and small interfering RNA (siRNA) for the treatment of bone diseases.