Volume: 2, Issue: 2
ABSTRACT
Antibiotics (AB), the term coined in the year 1941 has come a long way as an effective pharmacological agent in the history of integrative medicine. Antibiotic resistance is quite common which was observed for S.aureus within 5 years after introduction of first antibiotic i.e., penicillin in 1943. The truth is, the usage of AB has eventually resulted in resistance over time and are now rendered obsolete. Bacterial infection is tied to a large part of morbidity and mortality rates in medical practice and antibiotics have proved to be a boon resolving this problem. However, antibiotic resistance (ABR) has now become a massive issue with social, economic and health repercussions (1). Figure 1 depicts the mechanisms exploited by bacteria in order to tackle the action of antibiotic agents. The statistic claims that by 2050 the AMR population could reach over 10 million people thus exceedingly around 8.2 million lives which is currently accounted to cancer (2,3). This newsletter focuses on the therapeutic approaches and extensive attempts that are made to overcome for antibiotic resistance. Figure 2 depicts the underutilised tools such antibodies, stem cells, vaccines, immunomodulators and nanomedicines against antibiotic resistant.
