A bird eye view on Rasmussen Encephalitis

Rasmussen encephalitis (RE) is a rare and progressive neurological disorder primarily affecting children, characterized by chronic inflammation and unilateral brain atrophy. Diagnosis relies on clinical, electroencephalogram (EEG), magnetic resonance imaging (MRI), and histopathological criteria. Current treatments, including high-dose methylprednisolone, intravenous immunoglobulin’s (IVIg), and surgical interventions such as hemispherectomy, offer varying degrees of success in managing seizures and slowing disease progression. Adalimumab has shown efficacy in reducing seizure frequency. Ongoing patent activity underscores efforts to develop novel therapies. Enhanced research is essential to improve diagnostic precision and treatment outcomes for RE patients. Keywords: Rasmussen encephalitis, diagnosis, treatment, seizures, hemispherectomy, adalimumab, patents, neurological disorder.