Nephrotic syndrome: Rare chronic kidney disease

The rare disease "nephrotic syndrome" refers to a kidney illness that causes your body to discharge an excessive amount of protein in urine. Nephrons, which are around a million filtering units, make up the kidneys. Each nephron consists of a tubule and a filter known as a glomerulus. The tubule replenishes the blood with necessary chemicals and eliminates surplus water and wastes, resulting in urine, while the glomerulus filters the blood. Damage to the glomeruli causes excessive amounts of protein to seep from the circulation into the urine, which is often the cause of nephrotic syndrome (1). The term "nephrotic-range proteinuria" refers to the loss of protein up tothree grams or more through urine in a period of 24-houror the presence of two grams of protein for every gram of urine creatinine in a single urine sample (2).