Bone Targeted Drug Delivery Systems: Osteoporosis

Abstract Drugs used to treat bone diseases that are administered systemically frequently have poor drug absorption in the tissue they are intended to treat, the potential for systemic toxicity, and poor therapeutic outcomes. Numerous micro- and nano-sized drug carriers have been created in order to get around these restrictions and treat bone pathologies that have a particular affinity for bone. A targeted drug delivery system that can bind to bone and release therapeutics exactly where it is needed can be formed by functionalizing drug carriers with bone mineral seekers (BMS).