Volume: 4, Issue: 1

ABSTRACT

Menopause, a natural biological transition, significantly impacts women's health due to declining estrogen levels. This hormonal shift contributes to metabolic syndrome, cardiovascular disease, osteoporosis, vasomotor symptoms, mood disturbances, sleep disorders, and sexual dysfunction. Management strategies include menopausal hormone therapy (MHT), nonhormonal medications, and lifestyle interventions. While MHT remains the most effective treatment, risks such as breast cancer and thromboembolism necessitate individualized approaches. Emerging treatments, including estetrol and neurokinin 3 receptor antagonists, offer promising alternatives. Comprehensive care involving screening, symptom tracking, and risk assessment is crucial for improving postmenopausal quality of life. Keywords: Menopausal Hormone Therapy (MHT), Vasomotor Symptoms, Osteoporosis, Nonhormonal Treatment, Estetrol, Neurokinin 3 Receptor Antagonists